This question comes from a member of our Hair Loss Social Community and Discussion Forums:
After becoming concerned about my hair loss I started doing some research and found that dihydrotestosterone (DHT) is the hormone responsible for genetic baldness. Knowing this, I assume the best way to treat progressive hair loss is to “block” DHT? Is this true? Is DHT an important element of hair loss?
In my opinion, the best way to “block” DHT is to prevent it from forming in inappropriate amounts in the first place. Medications that block the activity of the 5-alpha-reductase enzyme (mainly type II 5-alpha-reductase), the compound responsible for converting testosterone to dihydrotestosterone, will greatly decrease the amount of DHT available to affect hair follicles and cease the progressive loss.
As of now, the two compounds known to block the 5-alpha-reductase activity are finasteride (the active ingredient in Propecia) and dutasteride (the active ingredient in Avodart). Of these two, finasteride is proven safe and effective for treating hair loss and, in my opinion, is the most effective compound to block DHT and prevent progressive baldness.
Blake Bloxham – formerly “Future_HT_Doc”
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